Adrenal hormone test

Testing for adrenal hormones is a laboratory examination used to assess adrenal gland function and identify hormonal disorders associated with hypofunction or hyperactivity. This test is essential for diagnosing conditions that affect metabolism, blood pressure, stress response, and electrolyte balance.

When is adrenal hormone testing required?

• In cases of chronic fatigue, weakness, or dizziness – possible adrenal insufficiency.
• With fluctuations in blood pressure, headaches, or palpitations – suspected disorders of catecholamine production.
• In weight gain, obesity, or metabolic disturbances – may be related to excess cortisol.
• With menstrual irregularities, hirsutism, or infertility – evaluation of adrenal androgens.
• When Addison’s disease or Cushing’s syndrome is suspected – diagnosis of endocrine pathologies.
• In chronic stress or depressive conditions – monitoring cortisol levels.

Which hormones are included in the analysis?

• Cortisol – the main stress hormone, regulating metabolism and immune response.
• Aldosterone – responsible for water–electrolyte balance and blood pressure regulation.
• Adrenaline and noradrenaline – catecholamines regulating cardiovascular function.
• Dehydroepiandrosterone sulfate (DHEA-S) – an androgen influencing reproductive function and metabolism.
• Renin – regulates blood pressure and kidney function.
• 17-OHP (17-hydroxyprogesterone) – a cortisol precursor, tested when congenital adrenal hyperplasia is suspected.

How is the test performed?

1. Preparation – blood is usually collected in the morning; stress and intense physical activity should be avoided the day before testing.
2. Sample collection – venous blood or 24-hour urine, depending on the hormone being analyzed.
3. Laboratory analysis – hormone concentrations are measured using immunoassay or mass spectrometry.
4. Results – typically available within 1–3 days.

Interpretation of adrenal hormone test results

• Elevated cortisol – may indicate Cushing’s syndrome, chronic stress, or obesity.
• Low cortisol – characteristic of Addison’s disease or adrenal insufficiency.
• Increased aldosterone – a sign of hyperaldosteronism and hypertension.
• Decreased aldosterone – seen in Addison’s disease or chronic kidney disease.
• High DHEA-S – may be associated with adrenal tumors, hirsutism, or polycystic ovary syndrome (PCOS).
• Excess adrenaline and noradrenaline – observed in pheochromocytoma, severe stress, or hypertension.

Main advantages of adrenal hormone testing in Belarus

• Early detection of endocrine disorders – allows identification at early stages.
• High diagnostic accuracy due to modern laboratory techniques.
• Hormonal balance monitoring – supports treatment adjustment and prevention of complications.
• Comprehensive assessment – evaluates adrenal function affecting multiple body systems.

The analysis is performed in leading laboratories in Belarus using advanced diagnostic technologies. Experienced endocrinologists assist with result interpretation and, when necessary, prescribe effective treatment.